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. 2021 Jan 4;131(1):e138332. doi: 10.1172/JCI138332

Figure 4. Expression of MMP9 in the dentate gyrus and CA1 of the rat hippocampus.

Figure 4

In controls rats, MMP9 was weakly expressed in neurons while it could not be detected in cells with glial morphology (A and B). In acute and latent phases, moderate MMP9 expression was seen in neurons and weak expression was seen in glia (C–F). During the chronic phase, moderate to high MMP9 expression was observed in neurons, while MMP9 could hardly be detected in cells with glial morphology (G–J). Scale bar: 50 μm. Arrowheads indicate positive cells with glial morphology. Arrows indicate positive neurons. Photographs are taken from representative cases of control (n = 5), acute (n = 5), latent (n = 6), chronic nonprogressive (n = 5), and chronic progressive (n = 6) animals.