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. 2021 Jan 4;131(1):e139700. doi: 10.1172/JCI139700

Figure 4. Odd ratios for the association of ABO genotypes and moderate or severe ARDS in iSPAAR.

Figure 4

Odds ratios for the association of ABO genotypes grouped by estimated antigen density and moderate or severe ARDS in the (A) overall iSPAAR sepsis case-control study and (B) nonpulmonary source and (C) pulmonary source of sepsis in the iSPAAR study. The point estimate represents the comparison of each ABO genotype grouping to the reference group, genetically inferred O blood type, adjusted for age, sex, acute physiology, and chronic health evaluation (APACHE) III score, history of diabetes, and history of malignancy. The error bars represent the 95% CI around each odds ratio. The iSPAAR study is a case-control study, not a cohort study, so we are unable to calculate standardized risks.