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. 2021 Jan 4;131(1):e138986. doi: 10.1172/JCI138986

Figure 10. ANGPTL2-SEVs support human AML development.

Figure 10

(A) The colony-forming ability of human AML cells after coculture with Ctrl-SEVs or ANGPTL2-SEVs (n = 3; the data represent the means ± SD; *P < 0.05, **P < 0.01, ***P < 0.001, Student’s t test). (B) Flow cytometry (left) and histogram (right) analysis of the percentages of human CD45+ AML cells in the PB of recipients injected with AML cells after coculture with Ctrl-SEVs or ANGPTL2-SEVs (n = 3–5; the data represent the means ± SD; *P < 0.05, **P < 0.01, Student’s t test). (C) Survival analysis of recipients injected with AML cells after coculture with Ctrl-SEVs or ANGPTL2-SEVs (n = 5; *P < 0.05, log-rank test). Experiments were conducted 2–3 times for validation.

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