Table 1. Low frequency of SNP variants in P. vivax drug resistance genes in Mauritania compared with other endemic populations.
| Percentage of isolates containing resistance-associated variants (with numbers in brackets) in: | |||||||
|---|---|---|---|---|---|---|---|
| Gene | Codon Allele | Mauritania | Ethiopia | Thailand | Indonesia | Mexico | Colombia |
| dhfr | F57L/I | 0 (0/89) | 0 (0/24) | 91 (88/97) | 82 (77/94) | 0 (0/20) | 0 (0/31) |
| S58R | 0 (0/87) | 94 (17/18) | 100 (104/104) | 99 (104/105) | 0 (0/20) | 97 (30/31) | |
| T61M | 0 (0/90) | 0 (0/24) | 91 (90/99) | 82 (77/94) | 0 (0/20) | 0 (0/31) | |
| S117N/T | 1 (1/98) | 100 (24/24) | 100 (102/102) | 99 (93/94) | 0 (0/20) | 97 (30/31) | |
| dhps | A553G | 0 (0/99) | 0 (0/24) | 98 (98/100) | 16 (16/97) | 100 (20/20) | 100 (31/31) |
| A383G | 2 (2/100) | 17 (4/24) | 100 (104/104) | 97 (106/109) | 0 (0/20) | 84 (26/31) | |
| mdr1 | Y976F | 14 (14/100) | 32 (6/19) | 13 (14/104) | 100 (111/111) | 0 (0/19) | 3 (1/29) |