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. Author manuscript; available in PMC: 2020 Dec 30.
Published in final edited form as: Methods Mol Biol. 2019;1960:227–236. doi: 10.1007/978-1-4939-9167-9_20

Figure 2. Communication deficits observed in MIA offspring.

Figure 2.

Pregnant C57BL/6 mice were treated with either PBS or 20 mg/kg PolyI:C at embryonic days 11.5 (E11.5) and 12.5 (E12.5). (A-B) Communicative deficits in 10-day-old pups were evaluated through recording of ultrasonic vocalizations (USVs). (A) Representative USV detection plots. (B) Total number of USVs emitted during 3 minutes of recording. Error bars depict mean ± s.e.m. ***P < 0.001 calculated by Student’s t-test. sec, seconds; kHz, kilohertz.