Skip to main content
. Author manuscript; available in PMC: 2020 Dec 30.
Published in final edited form as: Methods Mol Biol. 2019;1960:227–236. doi: 10.1007/978-1-4939-9167-9_20

Figure 4. MIA offspring display repetitive behaviors in the marble-burying test.

Figure 4.

Pregnant C57BL/6 mice were treated with either PBS or 20 mg/kg PolyI:C at E11.5 and E12.5. (A) Representative pictures depicting pretest marble layout and marbles buried by control and MIA mice after 15 minutes. (B) Marble burying index score was calculated based on the following scale: 1 for marbles covered >50% by bedding, 0.5 for ~50% covered, or 0 for anything less. Error bars depict mean ± s.e.m. ***P < 0.001 calculated by Student’s t-test.