Table 1.
Demographics, covariates, education and cognitive testing results of the study population. FTD, frontotemporal dementia; PPA, primary progressive aphasia; bvFTD, behavioural-variant FTD; HC, healthy control; SD, standard deviation; MMSE, mini-mental-state examination; TMT, Trail Making Test.
| FTD | PPA | bvFTD | HC | |
|---|---|---|---|---|
| Number of subjects | 66 | 42 | 24 | 24 |
| Age (y, mean ± SD) | 66.9 ± 8.3 | 68.9 ± 7.6 | 63.4 ± 9.3 | 64.5 ± 7.3 |
| Sex (♂ / ♀) | ♂ 33 / ♀ 33 | ♂ 18 / ♀ 24 | ♂ 15 / ♀ 9 | ♂ 15 / ♀ 9 |
| Education (y, mean ± SD) | 12.5 ± 3.0 | 12.7 ± 3.1 | 12.1 ± 2.9 | |
| Follow-up (m, mean ± SD) | 20.9 ± 19.8 | 25.5 ± 22.5 | 14.7 ± 13.7 | |
| Neuropsychological evaluation | ||||
| MMSE (mean ± SD) | 24.0 ± 5.5 | 23.2 ± 6.2 | 25.5 ± 4.0 | 30 ± 0 |
| TMT-A (mean ± SD) | 24.7 ± 24.9 | 15.3 ± 16.3 | 34.1 ± 28.9 | |
| TMT-B (mean ± SD) | 106.4 ± 77.3 | 72.2 ± 27.4 | 137.8 ± 95.0 | |
| Naming (mean ± SD) | 8.1 ± 4.6 | 5.6 ± 3.6 | 10.8 ± 4.0 | |
| Semantic verbal fluency (mean ± SD) | 8.7 ± 4.4 | 6.6 ± 3.5 | 11.0 ± 4.3 | |
| Phonetic verbal fluency (mean ± SD) | 9.1 ± 4.7 | 8.2 ± 2.7 | 10.0 ± 6.0 | |