TABLE 1.
Differences between of the hemodynamics, demographic data, renal function, electrolyte and routine blood examination parameters among various TRA groups.
| Overall | Non –TR patients | TRA increased groups | |||
| Parameters | (n = 491 Subgroup n1 = 283) | (n = 84) | Mild increased TR (n = 153) | ms-TR group (n = 46) | p value |
| Demographic data | |||||
| Age (years) | 52.54 ± 14.32 | 52.23 ± 12.50 | 53.22 ± 15.25 | 51.41 ± 14.19 | 0.719 |
| BMI (kg/m2) | 22.45 ± 3.56 | 22.54 ± 3.17 | 22.56 ± 3.79 | 21.87 ± 3.92 | 0.503 |
| Echocardiographic parameters | |||||
| LA (mm) | 38.41 ± 5.77 | 36.74 ± 4.75 | 38.02 ± 4.86 | 43.93 ± 6.58**## | <0.001 |
| LVDD (mm) | 49.30 ± 6.29 | 48.80 ± 5.25 | 48.92 ± 5.93 | 54.11 ± 7.18**## | <0.001 |
| RA (mm) | 37.15 ± 5.11 | 35.52 ± 3.78 | 36.43 ± 4.03 | 44.41 ± 5.36**## | <0.001 |
| RV (mm) | 35.46 ± 5.56 | 34.40 ± 3.40 | 34.90 ± 3.51 | 40.98 ± 5.03**## | <0.001 |
| PA (mm) | 23.82 ± 2.70 | 23.65 ± 2.44 | 23.68 ± 2.49 | 25.14 ± 2.58**## | 0.001 |
| IVS (mm) | 13.04 ± 8.57 | 12.65 ± 1.64 | 12.47 ± 1.57 | 12.22 ± 1.73 | 0.345 |
| IVS mobility | 6.00 (6.00–6.00) | 6.00 (6.00–6.00) | 6.00 (6.00–6.00) | 3.00 (6.00–6.00) **## | <0.001 |
| LVPW (mm) | 11.00 (10.00–12.00) | 11.00 (10.00–12.00) | 11.80 (10.00–12.00)* | 11.20 (10.00–12.00) | 0.144 |
| LVPW mobility | 10.00 (10.00–10.00) | 10.00 (10.00–10.00) | 10.00 (10.00–10.00) | 10.00 (7.00–10.00)**## | <0.001 |
| FS (%) | 34.00 (31.00–37.00) | 35.00 (32.00–37.00) | 34.00 (32.00–37.00) | 29.00 (18.75–33.25)**## | <0.001 |
| LVEF (%) | 60.83 ± 9.44 | 62.55 ± 8.01 | 62.28 ± 7.78 | 50.28 ± 13.93**## | <0.001 |
| SV (ml) | 75.10 ± 20.22 | 74.57 ± 15.53 | 78.41 ± 21.86 | 75.20 ± 18.43**## | 0.301 |
| TRV (cm/s) | 281.00 (243.00–336.00) | – | 265.00 (240.00–311.50) | 354.00 (322.00–384.25) | <0.001 |
| ΔP (mmHg) | 33.00 (22.00–46.00) | – | 28.00 (23.00–38.25) | 50.00 (40.50–59.00) | <0.001 |
| Renal function (n = 283) | |||||
| eGFR [mL/(min⋅1.73 m2)] | 10.47 (5.62–13.00) | 10.47 (5.88–12.04) | 10.03 (5.88–13.00) | 10.34 (5.28–13.50) | 0.981 |
| Cr (μmol/L) | 815.50 (618.40–1016.90) | 821.80 (618.92–1017.45) | 814.40 (598.00–998.25) | 817.35 (643.95–1126.22) | 0.448 |
| BUN (μmoI/L) | 21.75 ± 7.82 | 21.26 ± 7.64 | 21.77 ± 7.58 | 22.57 ± 8.98 | 0.659 |
| Electrolyte parameters | |||||
| Mg2+ (mmol/L) | 0.982 ± 0.158 | 0.983 ± 0.175 | 0.978 ± 0.153 | 0.991 ± 0.143 | 0.877 |
| K+ (mmol/L) | 4.79 ± 0.787 | 4.78 ± 0.72 | 4.78 ± 0.79 | 4.83 ± 0.89 | 0.944 |
| Ca2+ (mmol/L) | 2.15 (2.03–2.28) | 2.15 (2.05–2.280) | 2.15 (2.02–2.28) | 2.14 (1.97–2.36) | 0.957 |
| Na+(mmol/L) | 137.85 (136.40–139.80) | 138.40 (136.50–140.00) | 137.84 (136.35–140.0) | 137.35 (136.07–139.20) | 0.149 |
| Cl– (mmol/L) | 102.45 (99.60–105.30) | 102.45 (99.10–105.20) | 102.45 (99.60–105.50) | 102.45 (99.98–105.80) | 0.882 |
| TCO2 (mmol/L) | 20.66 (18.00–23.00) | 21.05 (18.78–23.95) | 20.50 (18.10–23.00) | 19.90 (16.75–22.02) | 0.075 |
| P (mmol/L) | 1.91 ± 0.64 | 1.96 ± 0.63 | 1.89 ± 0.62 | 1.91 ± 0.69 | 0.722 |
| Dialysis time (days) | 1230.00 (541.00–2549.00) | 1214.00 (497.00–2101.25 | 1312.00 (539.00–2619.00) | 1368.00 (555.750–2632.75) | 0.183 |
| Routine blood examination parameters | |||||
| RBC (1012/L) | 3.39 ± 0.72 | 3.37 ± 0.62 | 3.40 ± 0.73 | 3.39 ± 0.86 | 0.950 |
| Hb (g/dl) | 100.52 ± 19.42 | 99.98 ± 19.46 | 100.45 ± 19.07 | 101.74 ± 20.83 | 0.884 |
| Hct (L/L) | 31.85 ± 6.12 | 31.85 ± 6.07 | 31.70 ± 5.98 | 32.37 ± 6.78 | 0.809 |
| MCV (fl) | 95.14 ± 8.02 | 95.11 ± 8.11 | 94.75 ± 8.14 | 96.50 ± 7.46 | 0.431 |
| MCH (pg) | 30.03 ± 2.70 | 29.84 ± 2.57 | 30.03 ± 2.78 | 30.39 ± 2.65 | 0.547 |
| MCHC (g/dl) | 315.72 ± 12.98 | 313.92 ± 11.22 | 316.99 ± 13.97 | 314.79 ± 12.38 | 0.191 |
| RDW-CV (%) | 14.57 ± 1.65 | 14.65 ± 1.61 | 14.48 ± 1.71 | 14.69 ± 1.56 | 0.649 |
| RDW-SD (%) | 51.30 (47.00–55.40) | 51.84 (47.00–55.78) | 51.20 (46.75–54.15) | 51.47 (48.70–56.60) | 0.342 |
| PLT (109/L) | 167.00 (124.00–211.00) | 171.756 (127.50–212.50) | 165.00 (123.00–221.00) | 150.00 (126.75–197.75) | 0.258 |
| WBC (109/L) | 6.61 (5.22–8.18) | 6.44 (5.24–8.09) | 6.87 (5.22–8.40) | 6.07 (5.10–6.98) | 0.445 |
| EO (%) | 2.80 (1.60–4.70) | 2.65 (1.50–4.35) | 2.70 (1.50–4.85) | 3.35 (1.88–5.00) | 0.277 |
| BASO (%) | 0.500 (0.300–0.700) | 0.500 (0.200–0.700) | 0.500 (0.300–0.700) | 0.500 (0.200–0.800) | 0.763 |
| MONO (%) | 6.00 (4.60–7.50) | 6.05 (4.48–6.98) | 5.90 (4.55–7.60) | 6.38 (4.80–7.62) | 0.771 |
| NEU (%) | 71.43 ± 9.54 | 70.77 ± 9.82 | 72.16 ± 9.36 | 70.19 ± 9.59 | 0.352 |
| LYMP (%) | 17.78 ± 7.23 | 18.20 ± 6.87 | 17.16 ± 7.05 | 19.03 ± 8.37 | 0.249 |
p presents differences among various groups.
*: p < 0.05 compared with non-TR group; **: p < 0.01 compared with non-TR group; ##: p < 0.01 compared with mild increased TR group.