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. 2020 Dec 17;11:593295. doi: 10.3389/fmicb.2020.593295

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Copyright © 2020 Wen, Chen, Luo, Zhao, Shu, Su, Zhao, Huang and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Inhibition of ZFAS1 reduces the anti-apoptotic effect of pORF5 and the infectivity of C. trachomatis. (A) Knockdown of lncRNA ZFAS1. (B) The detection of apoptosis in ZFAS1-interfered cells after the apoptotic induction by TNF-α. (C) The apoptotic rate (right panel) was detected by Hoechst staining (left panel). (D) The apoptotic rate was detected by FACS. (E) Infectivity of C. trachomatis was tested after the knockdown of ZFAS1. ^∗P < 0.05; ^∗∗P < 0.01.