Table 3.
Dose-volume histogram comparisons for PTV and main OARs in IMRT plans.
| OARs | IMRT-N | IMRT-BM | IMRT-LS+OC | P* | ||
|---|---|---|---|---|---|---|
| IMRT-BM VS IMRT-N | IMRT-LS+OC VS IMRT-N | IMRT-LS+OC VS IMRT-BM | ||||
| PTV | ||||||
| Dmean (Gy) | 45.95 ± 0.11 | 45.96 ± 0.07 | 46.04 ± 0.14 | 0.253 | 0.001 | 0.005 |
| HI | 0.053 ± 0.005 | 0.053 ± 0.005 | 0.053 ± 0.005 | 0.334 | 1.000 | 0.334 |
| CI | 0.893 ± 0.022 | 0.891 ± 0.018 | 0.883 ± 0.023 | 0.384 | <0.001 | 0.006 |
| Bone marrow (BM) | ||||||
| V10 (%) | 86.37 ± 2.50 | 84.22 ± 1.48 | 80.99 ± 2.10 | 0.003 | <0.001 | <0.001 |
| V20 (%) | 72.30 ± 2.34 | 65.54 ± 2.13 | 58.26 ± 1.10 | <0.001 | <0.001 | <0.001 |
| V30 (%) | 50.44 ± 3.24 | 43.96 ± 1.76 | 35.97 ± 1.32 | <0.001 | <0.001 | <0.001 |
| V40 (%) | 21.04 ± 2.69 | 18.66 ± 2.04 | 14.71 ± 1.47 | <0.001 | <0.001 | <0.001 |
| Dmean (Gy) | 27.92 ± 0.86 | 26.12 ± 0.36 | 24.29 ± 2.55 | <0.001 | <0.001 | 0.025 |
| Small intestine | ||||||
| V10 (%) | 82.84 ± 4.60 | 83.04 ± 4.57 | 82.12 ± 4.25 | 0.276 | 0.056 | 0.013 |
| V20 (%) | 60.56 ± 6.29 | 63.43 ± 6.40 | 65.05 ± 5.62 | <0.001 | <0.001 | 0.027 |
| V30 (%) | 37.29 ± 7.38 | 37.73 ± 7.13 | 37.58 ± 7.37 | 0.164 | 0.528 | 0.745 |
| V40 (%) | 17.84 ± 5.52 | 18.18 ± 5.60 | 18.29 ± 5.44 | 0.007 | 0.026 | 0.513 |
| Dmax (Gy) | 47.00 ± 0.28 | 47.06 ± 0.19 | 47.16 ± 0.31 | 0.194 | 0.004 | 0.130 |
| Rectum | ||||||
| V10 (%) | 97.35 ± 2.96 | 97.68 ± 2.77 | 97.66 ± 2.88 | 0.018 | 0.019 | 0.839 |
| V20 (%) | 93.73 ± 3.70 | 93.94 ± 3.40 | 93.52 ± 3.30 | 0.327 | 0.404 | 0.072 |
| V30 (%) | 75.97 ± 3.99 | 76.12 ± 3.21 | 74.85 ± 3.91 | 0.877 | 0.256 | 0.177 |
| V40 (%) | 34.14 ± 4.99 | 34.56 ± 5.83 | 35.96 ± 6.85 | 0.602 | 0.125 | 0.212 |
| Dmax (Gy) | 45.46 ± 0.49 | 45.40 ± 0.50 | 45.70 ± 0.52 | 0.481 | 0.013 | <0.001 |
| Bladder | ||||||
| V10 (%) | 98.64 ± 1.73 | 98.15 ± 2.08 | 98.19 ± 1.98 | 0.261 | 0.140 | 0.830 |
| V20 (%) | 82.34 ± 2.58 | 82.41 ± 3.36 | 82.41 ± 3.69 | 0.891 | 0.904 | 0.998 |
| V30 (%) | 63.73 ± 3.30 | 64.55 ± 1.93 | 64.57 ± 2.01 | 0.324 | 0.385 | 0.965 |
| V40 (%) | 43.37 ± 4.40 | 43.20 ± 5.71 | 43.51 ± 5.21 | 0.618 | 0.669 | 0.471 |
| Spinal Cord | ||||||
| Dmax (Gy) | 34.10 ± 3.03 | 28.40 ± 4.88 | 17.70 ± 3.74 | <0.001 | <0.001 | <0.001 |
| Femoral head-L | ||||||
| V10 (%) | 76.19 ± 7.57 | 77.54 ± 8.25 | 78.96 ± 9.71 | 0.434 | 0.211 | 0.561 |
| V20 (%) | 38.42 ± 6.18 | 38.10 ± 5.55 | 37.61 ± 5.73 | 0.802 | 0.538 | 0.528 |
| V30 (%) | 14.41 ± 5.33 | 13.56 ± 5.23 | 11.74 ± 4.95 | 0.152 | 0.006 | 0.043 |
| V40 (%) | 0.794 ± 1.306 | 0.687 ± 1.290 | 0.687 ± 1.308 | 0.294 | 0.676 | 0.998 |
| Femoral head-R | ||||||
| V10 (%) | 73.84 ± 8.25 | 75.77 ± 6.80 | 77.25 ± 8.59 | 0.356 | 0.034 | 0.351 |
| V20 (%) | 33.70 ± 5.84 | 33.63 ± 6.81 | 34.06 ± 6.52 | 0.945 | 0.790 | 0.615 |
| V30 (%) | 11.93 ± 5.64 | 11.05 ± 5.24 | 10.44 ± 5.59 | 0.130 | 0.019 | 0.236 |
| V40 (%) | 1.043 ± 1.819 | 0.821 ± 1.645 | 0.564 ± 1.416 | 0.401 | 0.199 | 0.097 |
*P value was computed by paired t test.