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. 2020 Dec 17;11:612325. doi: 10.3389/fphys.2020.612325

TABLE 1.

Demographic and clinical features of the 105 subjects included in the study sample.

All subjects Controls PreHD HD
Subjects (n) 105 38 18 49
Sex (Male/Female) 50/55 23/15 3/15 24/25
Age (years), mean (SD) 45.64 (14.94) 41.95 (15.76) 37 (12.46) 51.61 (12.77)
Duration of disease (years), mean (SD) 3.75 (3.13)
UHDRS, mean (SD) 17.11 (21.02) 0.52 (0.87) 2.2 (2.14) 34.83 (18.16)
TFC, mean (SD) 10.80 (3.59) 13 (0) 13 (0) 8.41 (4.01)
Function: -Assessment Score, mean (SD) -Score Incomplete, mean (SD) -Independence in%, mean (SD) 21.26 (5.84) 21.26 (5.84) 89.38 (17.56) 25 (0) 25 (0) 100 (0) 25 (0) 25 (0) 100 (0) 17.31 (6.31) 17.31 (6.31) 78.14 (19.78)
SDMT: -Correct, mean (SD) -Errors, mean (SD) 32.03 (21.58) 0.43 (1.20) 44.81 (15.09) 0.08 (0.39) 45.55 (17.25) 0 (0) 13.54 (14.24) 0.96 (1.71)
VFT-Total Correct, mean (SD) 17.97 (10.78) 26.5 (8.71) 23.64 (6.00) 9.09 (5.34)
STROOP Color Naming: -Correct, mean (SD) -Errors, mean (SD) -Self-corrected, mean (SD) 58.38 (22.70) 0.23 (0.73) 0.46 (0.80) 76.62 (12.46) 0.08 (0.27) 0.35 (0.80) 67.82 (12.16) 0.64 (1.21) 0.82 (0.87) 40.31 (17.60) 0.22 (0.75) 0.44 (0.76)
STROOP Word Reading: -Correct, mean (SD) -Errors, mean (SD) -Self-corrected, mean (SD) 64.96 (25.93) 0.28 (1.37) 0.21 (0.66) 84.38 (14.32) 0.04 (0.20) 0.15 (0.46) 81 (13.01) 0.09 (0.30) 0 (0) 42.97 (18.79) 0.55 (2.00) 0.32 (0.87)
STROOP Interference: -Correct, mean (SD) -Errors, mean (SD) -Self-corrected, mean (SD) 34.48 (16.43) 1.13 (2.59) 1.39 (2.11) 44.68 (9.43) 0.76 (2.55) 0.72 (0.94) 46.55 (8.27) 0.45 (1.04) 0.73 (0.90) 18.33 (10.74) 1.83 (2.35) 2.36 (2.87)
PBAs: -Depression, mean (SD) -Irritability/Aggressiveness, mean (SD) -Psychosis, mean (SD) -Apathy, mean (SD) -Executive Function, mean (SD) 4.24 (5.91) 1.97 (3.84) 0.28 (1.26) 0.86 (2.16) 0.51 (1.90) 1.73 (3.29) 1.12 (2.69) 0 (0) 0.19 (0.80) 0.04 (0.20) 1.2 (2.04) 0.1 (0.32) 0 (0) 0 (0) 0 (0) 6.97 (6.90) 3.14 (4.69) 0.57 (1.75) 1.6 (2.83) 1 (2.63)
MMSE, mean (SD) 25.91 (4.70) 29.57 (0.85) 30 (0) 23.70 (4.67)