Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 17;19:153–160. doi: 10.1016/j.csbj.2020.12.016

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 3 — Heat map and Violin plots of pathways in patients with mild, moderate or severe disease. Pathways are: a) Complement and coagulation cascades, b) Cytokine-cytokine receptor interaction, c) JAK-STAT signaling pathway, d) TGF-beta signalling, e) Platelets activation, and f) Ribosome. Heat map depicts the log₂ fold change of differentially expressed gene (DEGs) of COVID-19 patients compared with controls. Genes included have a log₂ fold change of more than 1 and a p-adjusted value of <0.05. For every gene in a given pathway, the average counts per million (CPM) was calculated in cases with mild (n = 37), moderate (n = 10) and severe (n = 3) disease, and these CPM values (dark dots) were plotted (Violin plots) indicating median and quartiles as well as minima and maxima bounds. *Expression of ACE2 and TMPRSS2.

Fig. 3 — Heat map and Violin plots of pathways in patients with mild, moderate or severe disease. Pathways are: a) Complement and coagulation cascades, b) Cytokine-cytokine receptor interaction, c) JAK-STAT signaling pathway, d) TGF-beta signalling, e) Platelets activation, and f) Ribosome. Heat map depicts the log₂ fold change of differentially expressed gene (DEGs) of COVID-19 patients compared with controls. Genes included have a log₂ fold change of more than 1 and a p-adjusted value of <0.05. For every gene in a given pathway, the average counts per million (CPM) was calculated in cases with mild (n = 37), moderate (n = 10) and severe (n = 3) disease, and these CPM values (dark dots) were plotted (Violin plots) indicating median and quartiles as well as minima and maxima bounds. *Expression of ACE2 and TMPRSS2.