Table 3.
Characteristics of 96 literature cases derived from 64 articles.
| Characteristics included literature cases | Total cases | Extra pulmonary granulomatous disease cases (CVID+EGD) | Pulmonary granulomatous disease cases (CVID+PGD) |
|---|---|---|---|
| Number of patients | 95 (100%) | 44 (46.3%) | 51 (53.7%) |
| Ratio female/male | 2.2 (65/30) | 1.8 (28/16) | 2.6 (37/14) |
| Age of diagnosis CVID or age reported in article: • Average |
34.3 | 35.0 | 33.7 |
| • Min. of age | 2 | 4 | 2 |
| • Max. of age | 72 | 72 | 68 |
| Biopsy obtained for diagnosis granuloma (% of total number within group) | 79 (83.2% of 95) | 37 (84.1% of 44) | 42 (82.4% of 51) |
| Timing diagnosis granuloma vs diagnosis CVID known | 60 (63.2% of 95) | 30 (68.2% of 44) | 30 (58.8% of 51) |
| Granuloma diagnosed before diagnosis CVID | 22 (36.7%) | 9 (30.0%) | 13 (43.3%) |
| Granuloma diagnosed after diagnosis CVID | 38 (63.3%) | 21 (70.0%) | 17 (56.6%) |
| Timing diagnosis granuloma vs diagnosis CVID not known, or same time point | 35 (36.8% of 95) | 14 (31.8%) | 21 (41.2%) |
| Number of treatment courses administered for granulomatous disease | 117 (100%) | 53 (45.3%) | 64 (54.7%) |
Characteristics of literature derived cohort. Percentages are of relevant totals shown.