TABLE 1.

Relative abundance of the components of TCOL^a in the cells from the rifampicin surviving population with respect to those of NCOL^b in the MLP^c cells, as analysed using GC-MS.

Component	dRelative fold-increase in the RSP cells (w.r.t. MLP cells)
α-D-glucopyranoside	6.67
1, 2, 5-linked-mannitol	4.97
3, 4-linked mannose	2.22
Hexa-acetyl-mannitol	1.84
1, 2, 3-propanetriol	1.83
Methyl 1, 2, 3, 4-tetrahydronaphthalene-2-carboxylate	1.76
1, 3-di-iso-propylnaphthalene	1.73
1, 2, 4-linked arabinitol	1.68
D- (1, 2-linked mannitol)	1.58
1, 3-di-iso-propylnaphthalene	1.41
5-linked galactonitrile	1.30
Galactose pyranoside	1.11
1, 7-di-iso-propylnaphthalene	1.10
α- D-mannopyranoside	1.08

TCOL^a, thickened capsular outer layer; NCOL^b, normal capsular outer layer; MLP^c, mid-log phase. ^dThe percentage “relative abundance” of each compound in the capsular outer layer of MLP and rifampicin surviving population was independently determined from the GC-MS data. By comparing these values for each compound, the fold difference was calculated. Since it is a relative quantitation, normalization was not performed for the values with equal cell number/biomass or any internal standard.