Figure 1.

SpvB enhances bacterial pathogenicity in S. typhimurium infection. Streptomycin-pretreated mice were orally infected with the indicated S. typhimurium strains (1 × 10⁸ CFUs) for 48 h. (A–D) Salmonella counts (per gram of the sample) in liver (A), spleen (B), MLN (C), and colon (D) of infected mice (n = 5). (E) Representative H&E-stained images (scale bar, 50 µm) of liver, spleen and colon tissues from uninfected (control) mice or Salmonella-infected mice. Data are presented as the mean ± SEM. ***P < 0.001; **P < 0.01; *P < 0.05; ns, not significant.