Table 1.
Berberine bridge enzyme-like (BBE-like) proteins and FAD-linked oxidases.
| Identification code | Gene/protein | Substrate | Organism | Reference |
|---|---|---|---|---|
| At1g01980 | BBE1/OGOX4 | Oligogalacturonides | Arabidopsis thaliana | Benedetti et al., 2018 |
| At1g11770 | BBE2/OGOX3 | |||
| At1g26380 | BBE3/Fad-linked Oxidoreductase 1 | Indole-cyanohydrin | Rajniak et al., 2015 | |
| At1g26390 | BBE4 | nd | na | |
| At1g26400 | BBE5 | |||
| At1g26410 | BBE6 | |||
| At1g26420 | BBE7 | |||
| At1g30700 | BBE8 | Rodrigues Oblessuc et al., 2019 | ||
| At1g30710 | BBE9 | na | ||
| At1g30720 | BBE10 | |||
| At1g30730 | BBE11 | |||
| At1g30740 | BBE12 | |||
| At1g30760 | BBE13/Monolignol-oxidase 1 | Coumaryl alcohol Sinapyl alcohol Coniferyl alcohol |
Daniel et al., 2015 | |
| At1g34575 | BBE14 | nd | na | |
| At2g34790 | BBE15/Monolignol-oxidase 2 | Coumaryl alcohol Sinapyl alcohol Coniferyl alcohol |
Daniel et al., 2015 | |
| At2g34810 | BBE16 | nd | na | |
| At4g20800 | BBE17 | |||
| At4g20820 | BBE18 | |||
| At4g20830 | BBE19-BBE20/OGOX1 | Oligogalacturonides Tri-galacturonic acid Di-galacturonic acid |
Benedetti et al., 2018 | |
| At4g20840 | BBE21/OGOX2 | Oligogalacturonides | ||
| At4g20860 | BBE22/CELLOX | Cellohexaose Cellopentaose Cellotetraose Cellotriose Cellobiose |
Locci et al., 2019 | |
| At5g44360 | BBE23 | nd | na | |
| At5g44380 | BBE24 | |||
| At5g44390 | BBE25 | |||
| At5g44400 | BBE26 | |||
| At5g44410 | BBE27 | |||
| At5g44440 | BBE28 | Daniel et al., 2016 | ||
| A0A2K1JP57 | BBE1/Cellobiose-oxidase | Lactose Cellobiose |
Physcomitrella patens | Toplak et al., 2018 |
| Q84N20 + Q84N21 | NEC5/Nectarin 5 | D-Glucose |
Nicotiana langsdorffii X Nicotiana sanderae |
Carter and Thornburg, 2004 |
| Q8SA60 | Carbohydrate oxidase | Cellopentaose Cellotetraose Cellotriose Cellobiose Lactose Maltose D-Glucose D-Galactose D-Mannose D-Atrose |
Lactuca sativa | Custers et al., 2004 |
| Q8SA59 | Helianthus annuus | |||
| P30986 | BBE1/Reticuline oxidase | (S)-reticuline | Eschscholzia californica | Winkler et al., 2006 |
| A0A067GII5 | CISIN_1g043104mg/uronic acid oxidase | D-Galacturonic acid | Citrus sinensis | Wei et al., 2020 |
| Q6PW77 | Gluco-oligosaccharide oxidase | Cellopentaose Cellotetraose Cellotriose Cellobiose Maltoheptaose Maltohexaose Maltopentaose Maltotriose Maltobiose Maltose Lactose D-Glucose |
Sarocladium strictum | Lee et al., 2005 |
| D7PF15 | Gluco-oligosaccharide oxidase-VN | Xylotriose Xylobiose Cellotriose Cellobiose Maltose D-Glucose D-Mannose N-acetyl-Glucosamine D-Galactose D-Xylose |
Foumani et al., 2011 | |
| I1S2K2 | Chito-oligosaccharide oxidase | Chitotetraose Chitotriose Chitobiose Cellotetraose Cellotriose Cellobiose Lactose Maltose D-Glucose N-acetyl-Glucosamine |
Gibberella zeae | Heuts et al., 2007 |
| P0CS93 | Galactose oxidase | D-Galactose Methyl-D-Galactose Dihydroxyacetone Lactose Raffinose Melibiose Lactobionic acid |
Choosri et al., 2011 | |
| G2QG48 | Xylo-oligosaccharide oxidase | Xylotetraose Xylotriose Xylobiose Lactose Cellobiose D-Xylose |
Myceliophthora thermophila | Ferrari et al., 2016 |
| I1SB12 | Carbohydrate oxidase | Maltose Cellobiose Lactose D-Glucose Deoxy-Glucose D-Galactose D-Mannose D-Xylose |
Microdochium nivale | Kulys et al., 2001 |
| P93762 | Hexose (and Disaccharide) Oxidase | Cellobiose Maltose Lactose D-Glucose D-Galactose |
Chondrus crispus | Groen et al., 1997 |
Nomenclature of BBE-like proteins from Arabidopsis thaliana is in accordance with TAIR database (www.arabidopsis.org/) whereas the other FAD-linked oxidases are identified by their UNIPROT code (www.uniprot.org/). The substrate of each flavoenzyme is indicated. The amino acid sequences were used to generate the protein homology tree shown in Figure 4. (CELLOX, Cellodextrin Oxidase; nd, not determined; na, not available; OGOX, Oligogalacturonide Oxidase).