TABLE 3.
Comparison of gene clusters and core genes involved in antibiotic biosynthesis in strains ZF129 and ZF197 as well as strains HY96-2, SQR-21, SC2, and J.
| Antibiotic name | Type | Bioactive spectrum | Core gene clusters | ZF129 | ZF197 | HY96-2 | SQR-21 | SC2 | J |
| Fusaricidin | NRPS | Fungal, G+bacteria | fusA, fecS | FGY93_ RS07740-FGY93_ RS07940 | FQU75_ RS17055-FQU75_ RS17255 | C1A50_ RS00290-C1A50_ RS00500 | PPSQR21_ RS00295-PPSQR21_ RS00495 | PPSC2_ RS29015- PPSC2_ RS29230 | AOU00_ RS13080-AOU00_ RS13295 |
| Paenilarvins | TransATPKS-NRPS | Fungal | nrsABC | FGY93_ RS03150- FGY93_ RS03340 | NA | C1A50_ RS04650- C1A50_ RS04845 | PPSQR21_ RS04670-PPSQR21_ RS04860 | PPSC2_ RS33500- PPSC2_ RS33695 | NA |
| Polymyxin | NRPS | Bacteria | pmxABE | FGY93_ RS11650-FGY93_ RS11810 | NA | C1A50_ RS21330- C1A50_ RS21525 | PPSQR21_ RS21565-PPSQR21_ RS21745 | PPSC2_ RS50695- PPSC2_ RS50860 | AOU00_ RS09095-AOU00_ RS09245 |
| Tridecaptin | NRPS | G–bacteria | fusAA, pmxE | FGY93_ RS21870-FGY93_ RS22055 | FQU75_ RS02970-FQU75_ RS03155 | C1A50_ RS10840- C1A50_ RS11035 | PPSQR21_ RS10975-PPSQR21_ RS11160 | PPSC2_ RS40010- PPSC2_ RS40205 | AOU00_ RS24020-AOU00_ RS24185 |
| Bacitracin | NRPS | G+bacteria | nrpS1, nrpS2, leuA5 | NA | FQU75_ RS04550-FQU75_ RS04745 | C1A50_ RS24385 | NA | PPSC2_ RS53660 | AOU00_ RS00290- AOU00_ RS00485 |
| Kalimantacin/Aurantinins B-D | TransATPKS-Otherks-NRPS | G+bacteria | pksDEFJLMR | FGY93_ RS17410- FGY93_ RS17670 | NA | C1A50_ RS15500- C1A50_ RS15755 | PPSQR21_ RS15345- PPSQR21_ RS15595 | PPSC2_ RS44500- PPSC2_ RS44755 | AOU00_ RS03355- AOU00_ RS03630 |
| Paenilan | Lantipeptide | G+bacteria | spaC1, spaC2, bsaB | FGY93_ RS00440- FGY93_ RS00545 | NA | C1A50_ RS07485- C1A50_ RS07590 | PPSQR21_ RS07695- PPSQR21_ RS07800 | PPSC2_ RS36150- PPSC2_ RS36265 | NA |
| Paeninodin | Lassopeptide | Fungal, bacteria, virus | asnB | FGY93_ RS01940- FGY93_ RS02055 | FQU75_ RS22660- FQU75_ RS22780 | C1A50_ RS05950- C1A50_ RS06060 | PPSQR21_ RS05935- PPSQR21_ RS06045 | PPSC2_ RS34680- PPSC2_ RS34790 | AOU00_ RS18815- AOU00_ RS18925 |
| Paenibacillin | lanthipeptide | Fungal, bacteria | subBC | FGY93_ RS03415- FGY93_ RS03515 | NA | C1A50_ RS22090- C1A50_ RS22155 | PPSQR21_ RS22300- PPSQR21_ RS22365 | NA | AOU00_ RS09800- AOU00_ RS09865 |
| PaenicidinA/B | lanthipeptide | Fungal, bacteria | paeBC | FGY93_ RS09575- FGY93_ RS09670 | NA | C1A50_ RS23520- C1A50_ RS23615 | PPSQR21_ RS23745- PPSQR21_ RS23840 | NA | AOU00_ RS11260- AOU00_ RS11350 |
| Anabaenopeptin/nostamide | betalactone | bacteria | nrpS1, leuA | FGY93_ RS20370- FGY93_ RS20515 | NA | C1A50_ RS12640- C1A50_ RS12785 | PPSQR21_ RS12570- PPSQR21_ RS12715 | NA | NA |
| Paenibacterin | NRPS, T1PKS | Bacteria | grsB, tycC, pmxA, ituB, fusA | FGY93_ RS20840- FGY93_ RS21030 | FQU75_ RS05080- FQU75_ RS05250 | C1A50_ RS11960- C1A50_ RS12090 | PPSQR21_ RS12105- PPSQR21_ RS12250 | NA | NA |
| Surfactin | NRPS | Bacteria, virus | srfAA, nrsBC | NA | FQU75_ RS15390- FQU75_ RS15605 | NA | NA | NA | NA |
| Tauramamide | phosphonate | Bacteria | aepX | NA | FQU75_ RS15895- FQU75_ RS16115 | NA | NA | NA | NA |
| Unknown | NRPS | NA | fusAA | NA | FQU75_ RS03885- FQU75_ RS04030 | C1A50_ RS11755- C1A50_ RS11925 | NA | NA | AOU00_ RS24935- AOU00_ RS25105 |
| Unknown | NRPS, transAT-PKS | NA | FGY93_ RS02225- FGY93_ RS02475 | NA | C1A50_ RS05530- C1A50_ RS05785 | PPSQR21_ RS05515- PPSQR21_ RS05770 | NA | NA | |
| Unknown | Bacteriocin | NA | kinB1 | FGY93_ RS02640- FGY93_ RS02695 | FQU75_ RS22060- FQU75_ RS22115 | C1A50_ RS05290- C1A50_ RS05345 | PPSQR21_ RS05290- PPSQR21_ RS05345 | PPSC2_ RS34090- PPSC2_ RS34140 | AOU00_ RS18205- AOU00_ RS18260 |
| Unknown | NRPS-like | NA | lgrD | FGY93_ RS23885- FGY93_ RS24065 | FQU75_ RS01080- FQU75_ RS01265 | C1A50_ RS08985- C1A50_ RS09165 | PPSQR21_ RS09155- PPSQR21_ RS09335 | PPSC2_ RS38125- PPSC2_ RS38310 | AOU00_ RS22145- AOU00_ RS22310 |
NA, not available.