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Effects of JMF1907 and J4 on occurrence of seizure per day (A) and seizure duration (B) in the PTZ-induced kindling seizure model. Carbamazepine (CBZ, 4 mg kg– 1) was used as a reference. Data are given as mean ± SEM of five animals. Statistical analyses were calculated using the repeated measures two-way ANOVA followed by Fisher’s LSD test. Within days significances: * p < 0.05 compared to Ctrl group.
