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DJ-1 regulates the TRAF6-IRF5 pathway through P62 after cerebral I/R in rats. (A) DJ-1 affects the interaction between P62 and TRAF6 after cerebral I/R in rats. (B) Quantification of (A) P62 Co–IP intensity normalized to TRAF6 IP (compared to sham). (C–F) Western blot analysis of P62, TRAF6, IRF5, and IKKαβ levels in rats. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; n = 6 per group.
