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. 2020 Dec 17;8:593890. doi: 10.3389/fcell.2020.593890

FIGURE 9.

FIGURE 9

Mechanisms of DJ-1 regulating microglial/macrophage polarization. DJ-1 regulates microglial polarization in cerebral I/R. DJ-1 inhibits the expression of P62 and affects the interaction of P62-TRAF6. DJ-1 regulates the TRAF6/IRF5 signaling pathway through P62.