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. 2020 Dec 17;8:610544. doi: 10.3389/fbioe.2020.610544

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Copyright © 2020 Silini, Di Pietro, Lang-Olip, Alviano, Banerjee, Basile, Borutinskaite, Eissner, Gellhaus, Giebel, Huang, Janev, Kreft, Kupper, Abadía-Molina, Olivares, Pandolfi, Papait, Pozzobon, Ruiz-Ruiz, Soritau, Susman, Szukiewicz, Weidinger, Wolbank, Huppertz and Parolini.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Architecture of the human term placenta. General overview of the relationship between the basal decidua (maternal side/component of the human placenta) and the fetal side/component of the human placenta represented by the chorion frondosum, the chorionic plate and the fused amniotic membrane (placental portion). The residual portion of the amniotic membrane (reflected portion) adheres to the chorion laeve (so called because it is devoid of villi) which is in touch with the capsular decidua. The amniotic membrane surrounds the amniotic cavity containing amniotic fluid with different types of detached cells. The magnified scheme shows the different parts of the term placental architecture. hBD-MSC, human basal decidua-mesenchymal stromal cells; hAFC, human amniotic fluid cells; hAFSC, human amniotic fluid stem cells; hAF-MSC, human amniotic fluid-mesenchymal stromal cells.