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. 2020 Dec 17;8:610544. doi: 10.3389/fbioe.2020.610544

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Copyright © 2020 Silini, Di Pietro, Lang-Olip, Alviano, Banerjee, Basile, Borutinskaite, Eissner, Gellhaus, Giebel, Huang, Janev, Kreft, Kupper, Abadía-Molina, Olivares, Pandolfi, Papait, Pozzobon, Ruiz-Ruiz, Soritau, Susman, Szukiewicz, Weidinger, Wolbank, Huppertz and Parolini.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Structure of the chorion laeve. Histological images of human amnio-chorionic membrane (hACM) in correspondence of the chorion laeve (hCL) and the capsular decidua (hCD). Haematoxylin-eosin staining. (A) At low magnification (20x) a general overview of this portion of the amnio-chorionic membrane, which has a smooth appearance due to the absence of chorionic villi, is appreciable. (B) At higher magnification (40x) it is possible to appreciate more cell populations present in the chorion laeve including extravillous trophoblast (hCL-EVT) and mesenchymal stromal cells (hCL-MSC).