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. 2020 Oct 20;20:122–132. doi: 10.1016/j.omtm.2020.10.010

Figure 6.

Figure 6

Comparison of Binding and Internalization between AAV5 and MV Mutants

(A) Binding assay comparing binding of capsid to Huh7 cell surface between AAV5, MV18, and MV20. Data shown are mean values ± SD. ∗∗p < 0.01. (B) Internalization assay comparing amount of internalized virus in Huh7 cells between AAV5, MV18, and MV20. Data shown are mean values ± SD. ∗∗p < 0.01; ∗∗∗p < 0.001. (C) Percentage of bound viral genomes that are internalized comparison between AAV5, MV18, and MV20. Data shown are mean values ± SD. ∗p < 0.05; ∗∗p < 0.01. (D) Binding assay comparing binding of capsid to Huh7 cell surface between MV1, MV18, MV50, and MV53. Data shown are mean values ± SD. ∗∗p < 0.01. (E) Internalization assay comparing amount of internalized virus in Huh7 cells between MV1, MV18, MV50, and MV53. Data shown are mean values ± SD. (F) Percentage of bound viral genomes that are internalized comparison between MV1, MV18, MV50, and MV53. Data shown are mean values ± SD. ∗p < 0.05; ∗∗p < 0.01.