Table 1.

Subcellular localization of IRF3 in the presence of EBV BFRF1.

Host protein	Cells transfected with vector or BFRF1 expression plasmid	Cells treated with SeV	Total number of cells transfected with vector or BFRF1 expression plasmid	Subcellular localization pattern of IRF3 in cells transfected with vector or BFRF1 expression plasmid	Number of subcellular localization change of IRF3 in cells transfected with vector or BFRF1 expression plasmid	Percentage of subcellular localization change of IRF3 in cells transfected with vector or BFRF1 expression plasmid
IRF3	Vector	−	20	Pan-cytoplasmic	0	0
IRF3	Vector	+	20	Nuclear	1	5
IRF3	BFRF1-Myc	−	20	Pan-cytoplasmic	0	0
IRF3	BFRF1-Myc	+	20	Pan-cytoplasmic or pan-cellular	15	75

HeLa cells were transfected with Myc vector or BFRF1-Myc expression plasmid. At 24 h post-transfection, cells were treated with or without 100 HAU/ml SeV for 16 h. Then, cells were examined for the subcellular localization pattern of IRF3 by IFA.