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. 2020 Dec 15;11:595692. doi: 10.3389/fphar.2020.595692

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Copyright © 2020 Li, Cui, Cao, Li, Shi, Qin and Du

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PLS-DA score plots of C, M and APS (A); permutation test of C, M and APS (B); PLS-DA score plots of C, M and APS-I (C); permutation test of C, M and APS-I (D); PLS-DA score plots of C, M and APS-II (E); permutation test of C, M and APS-II (F); PLS-DA score plots of C, M and APS-III (G); permutation test of C, M and APS-III (H); OPLS-DA score plots of C and M (I); S-plot of C and M (J). C: Control group, M: Model group. 1 (Triangle) = M, 2 (circle) = C, 3 (4-plot star) = APS, 3 (inverted triangle) = APS-I, 3 (5-plot star) = APS-II, 3(diamond) = APS-III.