Table 3.
Comparison Between Different FAF Patterns in Patients With RPGR-RP
| Parameters | Hyper-AF Ring (n = 14) | Decreased FAF (n = 14) | P Value | |||
|---|---|---|---|---|---|---|
| Age, y | 17.5 ± 5.8 | 30.1 ± 14.6 | 0.006 | |||
| Self-reported age of onset, y | 5.5 ± 3.6 | 7.4 ± 4.9 | 0.247 | |||
| Disease length, y | 12.0 ± 5.8 | 22.7 ± 15.6 | 0.023 | |||
| Mean refractive error, D | −3.3 ± 0.7 | −4.7 ± 1.0 | 0.277 | |||
| High myopia | 4 (28.6%) | 7 (50.0%) | 0.220 | |||
| Typical RP | 7 (50.0%) | 7 (50.0%) | 1.000 | |||
| Vitreomacular alteration | 0 (0%) | 5 (35.7) | 0.020 | |||
| Detectable photopic ERG | 10 (71.4%) | 10 (71.4%) | 0.590 | |||
| Mean Difference | ||||||
| Estimation Beta (P Value) | ||||||
| Right Eye | Left Eye | Right Eye | Left Eye | Crude | Age-Adjusted | |
| BCVA (logMAR) | 0.15 ± 0.10 | 0.14 ± 0.09 | 0.41 ± 0.36 | 0.44 ± 0.34 | −0.43 (< 0.001) | −0.08 (0.126) |
| EZ-band width, µm | 1782.9 ± 556.9 | 1820.9 ± 702.6 | 855.1 ± 451.2 | 831.0 ± 390.9 | 843 (< 0.001) | 823 (< 0.001) |
| MMT, µm | 239.8 ± 39.6 | 237.4 ± 35.4 | 213.6 ± 43.8 | 211.9 ± 49.9 | 25.9 (0.089) | 28.9 (0.076) |
| Photopic ERG (b-wave amplitude), µV | 12.4 ± 17.3 | 15.3 ± 20.9 | 4.5 ± 8.1 | 4.3 ± 8.2 | 9.4 (0.067) | 6.9 (0.138) |
| Photopic ERG (b-wave implicit time), ms | 42.5 ± 3.1 | 42.6 ± 5.0 | 45.2 ± 1.7 | 44.7 ± 4.0 | −2.4 (0.194) | −3.5 (0.096) |
| 30 Hz Flicker ERG (trough-to-peak amplitude), µV | 13.8 ± 14.5 | 12.6 ± 9.8 | 5.9 ± 4.1 | 7.0 ± 5.3 | 6.7 (0.066) | 2.1 (0.455) |
| 30 Hz Flicker ERG (implicit time), ms | 44.2 ± 3.7 | 42.8 ± 2.4 | 50.9 ± 9.9 | 50.7 ± 9.8 | −7.2 (0.011) | −8.4 (0.037) |
| MS, dB | 4.8 ± 3.4 | 5.8 ± 3.6 | 2.2 ± 3.7 | 4.3 ± 5.6 | 2.0 (0.272) | 2.4 (0.111) |