Table 1.
The results of immune cell ssGSEA score in different gastric disease stages.
| ssGSEA score | ||||||
|---|---|---|---|---|---|---|
| NGM (mean ± SD) | SG (mean ± SD) | AG (mean ± SD) | EAG (mean ± SD) | T1/2 (mean ± SD) | T3/4 (mean ± SD) | |
| Immune cell | n = 5 | n = 6 | n = 9 | n = 10 | n = 51 | n = 187 |
| Activated B cell | −0.1886 ± 0.0677 | 0.0560 ± 0.0817 | 0.1638 ± 0.1933 | 0.1255 ± 0.1570 | −0.1911 ± 0.0276 | −0.1874 ± 0.0299 |
| Activated CD4 T cell | 0.0223 ± 0.0345 | 0.1635 ± 0.0497 | 0.2177 ± 0.0914 | 0.2339 ± 0.1082 | −0.0371 ± 0.0327 | −0.0397 ± 0.0329 |
| Activated CD8 T cell | 0.0574 ± 0.0193 | 0.1082 ± 0.0313 | 0.1312 ± 0.0497 | 0.1243 ± 0.0542 | 0.0324 ± 0.0326 | 0.0230 ± 0.0348 |
| Activated dendritic cell | 0.0330 ± 0.0123 | 0.1145 ± 0.0361 | 0.1065 ± 0.0333 | 0.1252 ± 0.0461 | 0.1790 ± 0.0265 | 0.1895 ± 0.0300 |
| CD56bright natural killer cell | 0.1508 ± 0.0072 | 0.1474 ± 0.0560 | 0.1592 ± 0.0208 | 0.1465 ± 0.0197 | −0.0411 ± 0.0372 | −0.0440 ± 0.0338 |
| CD56dim natural killer cell | 0.2835 ± 0.0438 | 0.2820 ± 0.0299 | 0.2823 ± 0.0164 | 0.2848 ± 0.0348 | −0.0125 ± 0.0546 | −0.0145 ± 0.0575 |
| Central memory CD4 T cell | 0.3917 ± 0.0119 | 0.4155 ± 0.0247 | 0.4323 ± 0.0268 | 0.4405 ± 0.0296 | 0.0583 ± 0.0306 | 0.0613 ± 0.0302 |
| Central memory CD8 T cell | 0.2562 ± 0.0175 | 0.2833 ± 0.0225 | 0.2722 ± 0.0616 | 0.3044 ± 0.0506 | 0.0139 ± 0.0342 | −0.0011 ± 0.0345 |
| Effector memory CD4 T cell | 0.2352 ± 0.0232 | 0.2293 ± 0.0134 | 0.2526 ± 0.0284 | 0.2693 ± 0.0464 | 0.2673 ± 0.0238 | 0.2682 ± 0.0263 |
| Effector memory CD8 T cell | 0.1404 ± 0.0250 | 0.2499 ± 0.0378 | 0.2728 ± 0.0549 | 0.2682 ± 0.0672 | 0.0029 ± 0.0317 | −0.0019 ± 0.0440 |
| Eosinophil | −0.0248 ± 0.0488 | 0.0020 ± 0.0185 | 0.0344 ± 0.0380 | 0.0182 ± 0.0516 | 0.1138 ± 0.0499 | 0.1291 ± 0.0418 |
| Gamma delta T cell | 0.1089 ± 0.0131 | 0.1237 ± 0.0506 | 0.1386 ± 0.0363 | 0.1682 ± 0.0418 | −0.0490 ± 0.0413 | −0.0492 ± 0.0364 |
| Immature B cell | −0.0151 ± 0.0373 | 0.2138 ± 0.1021 | 0.2867 ± 0.1829 | 0.2515 ± 0.1711 | 0.2568 ± 0.0376 | 0.2633 ± 0.0417 |
| Immature dendritic cell | 0.2110 ± 0.0236 | 0.2128 ± 0.0495 | 0.2282 ± 0.0411 | 0.2522 ± 0.0399 | −0.0430 ± 0.0315 | −0.0421 ± 0.0374 |
| Macrophage | −0.1931 ± 0.0249 | −0.1438 ± 0.0359 | −0.1215 ± 0.0482 | −0.1038 ± 0.0588 | 0.0786 ± 0.0359 | 0.0661 ± 0.0350 |
| Mast cell | −0.1473 ± 0.0403 | −0.1244 ± 0.0655 | −0.1120 ± 0.0502 | −0.0799 ± 0.0504 | 0.1089 ± 0.0372 | 0.0838 ± 0.0491 |
| MDSC | −0.0457 ± 0.0253 | 0.0986 ± 0.0803 | 0.1239 ± 0.0972 | 0.1271 ± 0.1007 | 0.0035 ± 0.0380 | −0.0081 ± 0.0347 |
| Memory B cell | 0.0418 ± 0.0201 | 0.1163 ± 0.0277 | 0.1556 ± 0.0548 | 0.1611 ± 0.0585 | 0.0537 ± 0.0555 | 0.0769 ± 0.0572 |
| Monocyte | 0.3280 ± 0.0174 | 0.3412 ± 0.0185 | 0.3535 ± 0.0274 | 0.3631 ± 0.0295 | 0.0384 ± 0.0277 | 0.0411 ± 0.0352 |
| Natural killer cell | 0.2295 ± 0.0099 | 0.2465 ± 0.0826 | 0.2763 ± 0.0222 | 0.2829 ± 0.0355 | −0.0710 ± 0.0334 | −0.0567 ± 0.0317 |
| Natural killer T cell | −0.0742 ± 0.0161 | −0.0469 ± 0.0235 | −0.0224 ± 0.0302 | −0.0071 ± 0.0344 | 0.0974 ± 0.0323 | 0.0772 ± 0.0350 |
| Neutrophil | −0.3628 ± 0.0456 | −0.2964 ± 0.0326 | −0.2511 ± 0.0413 | −0.2153 ± 0.1083 | −0.0390 ± 0.0295 | −0.0366 ± 0.0312 |
| Plasmacytoid dendritic cell | 0.2317 ± 0.0121 | 0.2553 ± 0.0171 | 0.2507 ± 0.0352 | 0.2659 ± 0.0159 | −0.0220 ± 0.0403 | −0.0209 ± 0.0324 |
| Regulatory T cell | 0.0212 ± 0.0207 | 0.1503 ± 0.0348 | 0.1577 ± 0.0715 | 0.1788 ± 0.0989 | 0.0493 ± 0.0494 | 0.0385 ± 0.0426 |
| T follicular helper cell | 0.0345 ± 0.0130 | 0.0631 ± 0.0318 | 0.0798 ± 0.0223 | 0.0757 ± 0.0352 | 0.0822 ± 0.0220 | 0.0868 ± 0.0236 |
| Type 1 T helper cell | 0.0196 ± 0.0077 | 0.0639 ± 0.0151 | 0.0821 ± 0.0317 | 0.0848 ± 0.0321 | −0.1250 ± 0.0183 | −0.1226 ± 0.0218 |
| Type 17 T helper cell | −0.0142 ± 0.0184 | −0.0172 ± 0.0393 | 0.0074 ± 0.0189 | −0.0082 ± 0.0194 | −0.0332 ± 0.0281 | −0.0295 ± 0.0341 |
| Type 2 T helper cell | 0.1720 ± 0.0200 | 0.2071 ± 0.0167 | 0.2185 ± 0.0296 | 0.2372 ± 0.0284 | 0.1276 ± 0.0265 | 0.1146 ± 0.0285 |