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The effect of single oral administration of CPS, SPS and furosemide on the urine output of saline-loaded rats. Urine output was measured at 1, 2, 3, 4, 5, and 6 h post-administration. The cumulative values are expressed as the mean ± SE of eight rats in every group. *p < 0.05; **p < 0.01 compared to the M group using the Student’s t-test.
