Figure 1.

Antibody dynamics in patients with severe acute respiratory syndrome coronavirus 2, United Kingdom, 2020. A) NOD by days after first positive PCR result. Blue indicates seroconverting patients; red indicates nonseroconverting patients. B) Mean (± SEM) NODs (>3 samples per time point; n = 48) by days after first positive PCR result for those who seroconverted. A 4-parameter sigmoidal unconstrained model is shown (r² = 0.45). C) Mean (± SEM) NODs (>3 per time point; n = 45) by days after symptom onset for patients who seroconverted. A 4-parameter sigmoidal unconstrained model is shown (r² = 0.63). NOD, normalized optical density.