Table. Recreational water–associated primary amebic meningoencephalitis, United States, 1978–2018.

Years	No. cases	Median latitude, decimal degrees (range)	p value*
1978–1989	20	30.3 (27.8–38.0)	Referent
1990–1999	15	32.5 (26.5–35.5)	0.90
2000–2009	26	32.3 (28.1–36.1)	0.47
2010–2018	24	33.6 (26.1–45.0)	0.02

*Pairwise comparison to reference group using Dwass-Steel-Critchlow-Fligner test.