TABLE 1.
Univariate regression analysis was performed on the OS of 9 genes and BRCA patients in training sets
| Genes | GSE26085 | GSE42568 | GSE20711 | GSE88770 | ||||
|---|---|---|---|---|---|---|---|---|
| HR(95%CI) | p‐value | HR(95%CI) | p‐value | HR(95%CI) | p‐value | HR(95%CI) | p‐value | |
| STXBP3 | 0.27 (0.12‐0.60) | 1.46E−03 | 0.17 (0.08‐0.37) | 4.46E−06 | 0.12 (0.03‐0.45) | 1.91E−03 | 0.12 (0.03‐0.51) | 4.01E−03 |
| PKN2 | 0.58 (0.34‐0.99) | 4.86E−02 | 0.31 (0.14‐0.69) | 3.83E−03 | 0.24 (0.07‐0.88) | 3.08E−02 | 0.16 (0.03‐0.95) | 4.38E−02 |
| TCAP | 1.69 (1.25‐2.28) | 5.91E−04 | 1.86 (1.16‐2.97) | 9.81E−03 | 2.38 (1.35‐4.19) | 2.74E−03 | 6.87 (1.61‐29.21) | 9.08E−03 |
| STARD3 | 1.33 (1.12‐1.58) | 1.36E−03 | 1.64 (1.20‐2.25) | 1.96E−03 | 1.35 (1.04‐1.74) | 2.31E−02 | 1.62 (1.01‐2.60) | 4.69E−02 |
| CDR2L | 1.66 (1.21‐2.29) | 1.91E−03 | 2.09 (1.32‐3.32) | 1.74E−03 | 2.02 (1.13‐3.63) | 1.79E−02 | 5.89 (2.21‐15.70) | 3.85E−04 |
| PNMT | 1.20 (1.04‐1.38) | 1.26E−02 | 1.35 (1.09‐1.67) | 5.41E−03 | 1.44 (1.21‐1.72) | 4.71E−05 | 2.01 (1.23‐3.29) | 5.26E−03 |
| GPR4 | 2.46 (1.15‐5.26) | 2.02E−02 | 7.63 (2.85‐20.39) | 5.14E−05 | 13.26 (2.21‐79.45) | 4.65E−03 | 6.03 (1.80‐20.26) | 3.65E−03 |
| ANGPT2 | 1.56 (1.07‐2.26) | 2.08E−02 | 4.05 (1.60‐0.25) | 3.09E−03 | 2.41 (1.21‐4.81) | 1.28E−02 | 2.70 (1.13‐6.46) | 2.54E−02 |
| CAPN5 | 1.69 (1.08‐2.63) | 2.11E−02 | 6.00 (2.20‐16.41) | 4.78E−04 | 4.50 (2.12‐9.55) | 9.16E−05 | 2.49 (1.09‐5.69) | 3.13E−02 |