Table 1.

Proposed mechanism of cancer chemoprevention

Proposed mechanism of cancer chemoprevention
Mechanisms of tumor‐blocking agents	Mechanisms of tumor‐suppressing agents
Scavenging of reactive oxygen species (ROS)	Alteration in gene expression
Modulation of antioxidant defense system	Inhibition of cell proliferation/clonal expansion
Induction of phase II drug‐metabolising enzymes	Induction of apoptosis
Inhibition of phase I drug‐metabolising enzymes	Induction of terminal differentiation/senescence
Induction of DNA repair	Modulation of signal transduction pathways
Blockade of carcinogen uptake