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. 2020 Dec 31;14(12):e0008905. doi: 10.1371/journal.pntd.0008905

Fig 1. The eye and the BRBs.

Fig 1

(A) The internal BRB isolates ocular tissues from the blood stream via tightly sealed endothelial cells, surrounded by pericytes, and Müller cell and astrocyte extensions. (B) The retina displays a stratified organization reflecting the localization of the different cell types fulfilling specific roles. The choroidal vascular system is separated from photoreceptor cells by tightly connected RPE cells, which adhere with their vascular pole to the basal Bruch membrane, forming the external BRB. BRB, blood-retinal barrier; RPE, retinal pigmented epithelial.