Table 1. Differentially abundant bacterial species before and after the onset of tumor in BSp-fed, GTPs-fed and combination-fed mice versus control-fed mice of the both BE and LC groups.
| Pre-tumor BE group | |||||||||
| Phylum; Class; Order; Family; Genus; Species | BSp | GTPs | Combination | ||||||
| Log2FC | p-value | qc | Log2FC | p-value | qc | Log2FC | p-value | qc | |
| Firmicutes; Clostridia; Clostridiales; Lachnospiraceae | 8.35 | 4.73E-24 | 6.39E-22 | -3.17 | 1.33E-07 | 1.07E-05 | 7.18 | 9.87E-19 | 2.00E-16 |
| Bacteroidetes; Bacteroidia; Bacteroidales; S24-7 | 2.63 | 2.15E-10 | 3.78E-09 | -8.56 | 2.59E-13 | 1.05E-10 | 3.05 | 1.00E-13 | 4.05E-12 |
| Firmicutes; Clostridia; Clostridiales; Ruminococcaceae | 3.92 | 1.14E-19 | 7.73E-18 | 3.32 | 2.91E-09 | 3.93E-07 | 4.75 | 1.66E-08 | 2.31E-14 |
| Post-tumor BE group | |||||||||
| Phylum; Class; Order; Family; Genus; Species | BSp | GTPs | Combination | ||||||
| Log2FC | p-value | qc | Log2FC | p-value | qc | Log2FC | p-value | qc | |
| Bacteroidetes; Bacteroidia; Bacteroidales; S24-7 | 5.72 | 4.64E-06 | 0.00011 | 10.56 | 0.000028 | 0.0043 | 3.99 | 0.00025 | 0.0052 |
| Actinobacteria; Coriobacteriia; Coriobacteriales; Coriobacteriaceae; Adlercreutzia | 2.15 | 0.00049 | 0.00458 | 1.53 | 0.00062 | 0.0078 | 4.94 | 2.38E-06 | 0.0076 |
| Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae; Lactobacillus | 11.77 | 6.75E-26 | 1.58E-23 | 11.25 | 6.33E-25 | 2.96E-22 | 11.65 | 1.97E-22 | 5.81E-20 |
| Firmicutes; Clostridia; Clostridiales; Lachnospiraceae | 9.12 | 2.59E-12 | 4.05E-10 | 3.32 | 0.00006 | 0.0074 | 6.17 | 4.28E-08 | 6.31E-06 |
| Firmicutes; Clostridia; Clostridiales; Ruminococcaceae; Ruminococcus | 6.60 | 0.00035 | 0.0035 | 1.11 | 0.0042 | 0.0015 | 6.45 | 0.00048 | 0.0084 |
| Pre-tumor LC group | |||||||||
| Phylum; Class; Order; Family; Genus; Species | BSp | GTPs | Combination | ||||||
| Log2FC | p-value | qc | Log2FC | p-value | qc | Log2FC | p-value | qc | |
| Bacteroidetes; Bacteroidia; Bacteroidales; S24-7 | 5.54 | 1.28E-25 | 4.40E-23 | 28.39 | 9.43E-46 | 2.05E-43 | 12.92 | 2.90E-25 | 9.96E-23 |
| Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae; Lactobacillus; reuteri | 9.06 | 5.97E-24 | 1.02E-21 | 17.71 | 1.65E-15 | 1.19E-13 | 9.84 | 3.85E-24 | 6.61E-22 |
| Post-tumor LC group | |||||||||
| Phylum; Class; Order; Family; Genus; Species | BSp | GTPs | Combination | ||||||
| Log2FC | p-value | qc | Log2FC | p-value | qc | Log2FC | p-value | qc | |
| Bacteroidetes; Bacteroidia; Bacteroidales; S24-7 | 8.26 | 2.37E-32 | 8.66E-30 | 6.04 | 5.39E-18 | 6.36E-16 | 8.12 | 2.49E-31 | 9.08E-29 |
| Firmicutes; Clostridia; Clostridiales; Lachnospiraceae | 5.94 | 1.13E-09 | 4.59E-08 | 25.10 | 1.36E-05 | 0.00053 | 7.88 | 4.88E-10 | 1.48E-08 |
| Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae; Lactobacillus; reuteri | 6.88 | 3.16E-14 | 2.30E-12 | 7.60 | 7.14E-05 | 0.0016 | 9.87 | 6.54E-21 | 5.97E-19 |
| Actinobacteria; Coriobacteriia; Coriobacteriales; Coriobacteriaceae; Adlercreutzia | 1.61 | 3.25E-06 | 5.65E-05 | 4.82 | 3.41E-05 | 0.001 | 9.50 | 7.94E-14 | 1.7E-11 |
qc represents FDR adjusted p-value.