Table 4. Adjusted Hazard Ratios (aHR) on patient mortality and graft failure*.
Characteristics at transplant | Patient mortality | Graft failure | |||||||
---|---|---|---|---|---|---|---|---|---|
aHR | 95% CI | P value | aHR | 95% CI | P value | ||||
Age | 1.019 | 1.017 | 1.02 | <.0001 | 1.009 | 1.008 | 1.01 | <.0001 | |
Gender (Ref = Male) | Female | 0.894 | 0.867 | 0.922 | <.0001 | 0.897 | 0.871 | 0.924 | <.0001 |
Race (Ref = White) | Asian | 0.699 | 0.645 | 0.757 | <.0001 | 0.712 | 0.66 | 0.768 | <.0001 |
Black | 1.258 | 1.201 | 1.318 | <.0001 | 1.267 | 1.213 | 1.324 | <.0001 | |
Hispanic | 0.878 | 0.839 | 0.92 | <.0001 | 0.895 | 0.857 | 0.935 | <.0001 | |
Others/Unknown | 0.985 | 0.859 | 1.13 | 0.83 | 0.969 | 0.851 | 1.103 | 0.63 | |
Body Mass Index | 0.994 | 0.992 | 0.997 | <.0001 | 0.996 | 0.993 | 0.998 | 0.0007 | |
MELD score | 0.994 | 0.992 | 0.996 | <.0001 | 0.994 | 0.992 | 0.996 | <.0001 | |
Dialysis prior week to transplant (Ref = N) | Yes | 1.337 | 1.261 | 1.417 | <.0001 | 1.303 | 1.233 | 1.378 | <.0001 |
Diabetes type 2 (Ref = N) | Yes | 1.165 | 1.122 | 1.21 | <.0001 | 1.112 | 1.072 | 1.153 | <.0001 |
Albumin | 0.941 | 0.922 | 0.96 | <.0001 | 0.936 | 0.918 | 0.954 | <.0001 | |
Encephalopathy is 3–4 (Ref = N) | Yes | 1.115 | 1.065 | 1.167 | <.0001 | 1.083 | 1.037 | 1.132 | 0.0004 |
KPS categories at (Ref = 80–100) | 10–40 | 1.184 | 1.126 | 1.244 | <.0001 | 1.109 | 1.058 | 1.162 | <.0001 |
50–70 | 1.11 | 1.069 | 1.152 | <.0001 | 1.076 | 1.039 | 1.114 | <.0001 | |
Donor Risk Index | 1.274 | 1.236 | 1.313 | <.0001 | 1.346 | 1.309 | 1.385 | <.0001 | |
Medical condition (Ref = Not hospitalized) | Hospitalized not in ICU | 1.072 | 1.02 | 1.128 | 0.006 | 1.073 | 1.023 | 1.126 | 0.004 |
In intensive care unit | 1.289 | 1.21 | 1.372 | <.0001 | 1.304 | 1.23 | 1.384 | <.0001 |
*Clinical variables at the time of liver transplantation.
KPS—Karnofsky Performance Status; MELD—model for end-stage liver disease.