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. 2020 Dec 31;15(12):e0244612. doi: 10.1371/journal.pone.0244612

Table 2. Associations of CRP with memory and verbal fluency trajectories.

logCRP
Unadjusted Model Adjusted Model 1 Adjusted Model 2 Adjusted Model 3
Initial Level Slope Initial Level Slope Initial Level Slope Initial Level Slope
Memory -.039(.013)** .001(.002) -.036(.012)** .001(.002) -.027(.013)* .002(.002) -.005(.013) .001(.002)
Fluency -.195(.013)*** .004(.002)* -.077(.012)*** .002(.002) -.061(.012)*** .002(.002) -.042(.013)** .003(.002)
90th Percentile CRP
Unadjusted Model Adjusted Model 1 Adjusted Model 2 Adjusted Model 3
Initial Level Slope Initial Level Slope Initial Level Slope Initial Level Slope
Memory -.026(.022) .001(.003) -.077(.021)*** -.001(.004) -.066(.021)** -.001(.004) -.045(.022)* -.001(.004)
Fluency -.132(.021)*** -.001(.003) -.089(.020)*** -.003(.003) -071(.020)*** -.003(.003) -.052(.021)* -.003(.003)

Note. Values reflect unstandardized parameter estimates (standard error); adjusted model 1 includes all demographic covariates; adjusted model 2 includes the health behavior covariates; adjusted model 3 added vascular risk factors;

*p < .05,

**p < .01,

***p < .001. CRP = C reactive protein.