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. 2020 Dec 31;15(12):e0244514. doi: 10.1371/journal.pone.0244514

Table 4. Odds Ratio (OR) and 95% confidence interval (95%CI) for NAFLD and advance fibrosis among groups of nut-consumers using binary logistic regression analyses adjusted for potential confounders.

Overall cohort NAFLD
aOR (95% CI) P value P value for linear trend aOR (95% CI) P value P value for linear trend
NAFLD <1 time/week reference reference 0.016 - - -
1–6 times/week 0.923 (0.770–1.106) 0.384 - - -
≥1 time/day 0.719 (0.558–0.926) 0.011 - - -
Fib-4 score >2.67 <1 time/week reference reference 0.110 reference reference 0.099
1–6 times/week 0.551 (0.338–0.898) 0.017 0.275 (0.112–0.678) 0.005
≥1 time/day 0.780 (0.427–1.423) 0.418 0.844 (0.337–2.110) 0.716
Forns-Index >6.9 <1 time/week reference reference 0.002 reference reference 0.001
1–6 times/week 0.585 (0.402–0.850) 0.005 0.384 (0.226–0.653) <0.001
≥1 time/day 0.533 (0.304–0.934) 0.028 0.450 (0.198–1.023) 0.057

Analyses were based on the overall cohort and NAFLD patients.

Displayed OR are adjusted for sex, age, BMI, metabolic syndrome, hepatic steatosis, alcohol consumption, intake of fast-food, vegetables, fruits, sweets, red and processed meat, white meat, fish, coffee and consumption of SSB. OR for Fib-4 score and Forns-Index were not adjusted for age since this variable is included in these indices.

Abbreviations: aOR–adjusted Odds ratio; NAFLD–non-alcoholic fatty liver disease; SSB–sugar-sweetened beverage; T2DM–type 2 diabetes mellitus; 95%CI– 95% confidence interval.