Table 3. Factors associated with false-negative RDT results using PCR as a reference.
Variable | RDT-/PCR+/False-negative | Univariable | Multivariable | ||
---|---|---|---|---|---|
n (%) | OR (95% CI) | p-value | aOR (95% CI) | p-value | |
Age (year) | |||||
≥5 | 108 (55.7) | 1 (Reference) | 0.179 | 1 (Reference) | |
<5 | 87 (63.0) | 1.36 (0.87–2.13) | 1.35 (0.83–2.19) | 0.224 | |
Parasite density (μL) | |||||
≥1000 | 105 (51.0) | 1 (Reference) | 1 (Reference) | ||
<1000 | 90 (71.4) | 2.4 (1.51–3.89) | 0.001 | 2.65(1.62–4.38) | 0.001 |
Gene deletion | |||||
No deletion | 171 (56.4) | 1 (Reference) | 1 (Reference) | ||
pfhrp 2/3 deletion | 24 (82.8) | 3.71 (1.49–11.23) | 0.01 | 4.4 (1.72–13.66) | 0.004 |
Parasite species | |||||
P. falciparum | 165 (55.0) | 1 (Reference) | 1 (Reference) | ||
Non-P. falciparum | 37.0 (93.9) | 12.76 (3.77–79.7) | 0.001 | 18.65 (5.3–118.71) | 0.001 |
Endemicity | |||||
Moderate | 63 (61.2) | 1 (Reference) | 1 (Reference) | ||
Low | 132 (57.6) | 1.16 (0.72–1.87) | 0.547 | 1.19 (0.63–2.24) | 0.595 |
Region | |||||
Western | 95 (57.6) | 1 (Reference) | 1 (Reference) | ||
Eastern | 100 (59.9) | 0.91 (0.59–1.41) | 0.67 | 0.83 (0.45–1.5) | 0.527 |
OR = unadjusted odds ratio, aOR = adjusted odds ratio.