TABLE 5.

The detailed information of compounds from Xiao-Xu-Ming Decoction.

Compound	Targets	Inhibition (%) against AChE	CDOCKER interaction energy of compounds interacting with AChE
Baicalein	ALOX12, ACAT1, APP, BACE1, CDK5, PTGS2, ESR1, GABRG1, GSK3B, MAOB, TNF	3.35	41.0117
Chrysin	ALOX12, APP, BACE1, CDK5, PTGS2, ESR1, GABRG1, GSK3B, MAPK10, MAOB, TNF	−1.31	40.5337
Dauricine	ALOX12, HTR1A, HTR3A, HTR6, ACHE, APP, BCHE, PTGS2, GABRG1, PDE4B, SIGMAR1	42.06	84.4849
Fangchinoline	HTR1A, HTR3A, HTR6, ACHE, CHRNA7, APP, BCHE, PTGS2, GABRG1, PDE4B, SIGMAR1	72.13	55.9794
Oroxylin A	ALOX12, ACHE, APP, BACE1, CDK5, PTGS2, ESR1, GABRG1, GSK3B, MAOB, MAPT, TNF	−2.99	46.1022
Quercetin	ALOX12, ACHE, APP, CDK5, PTGS2, ESR1, GABRG1, GSK3B, MAPK10, MAOB, MAPT, TNF	−4.96	43.9071
Wogonin	ALOX12, ACHE, APP, BACE1, CDK5, PTGS2, ESR1, GABRG, GSK3B, MAOB, MAPT, TNF	7.98	41.485