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. 2020 Dec 31;15(12):e0243467. doi: 10.1371/journal.pone.0243467

Table 1. Baseline demographic and clinical characteristics of variables used for prediction.

Overall No Yes P-value
n 1962 1642 320
Sex = Male (%) 778 (39.7) 702 (42.8) 76 (23.8) <0.001
Age (mean (SD)) 18.36 (3.57) 18.52 (3.64) 17.52 (3.11) <0.001
History of self-harm = Yes (%) 883 (45.0) 616 (37.5) 267 (83.4) <0.001
History of suicide ideation = Yes (%) 953 (48.6) 731 (44.5) 222 (69.4) <0.001
SOFAS (mean (SD)) 62.43 (9.02) 62.75 (9.06) 60.76 (8.62) <0.001
NEET = Yes (%) 307 (15.6) 264 (16.1) 43 (13.4) 0.269
Clinical stage (%) <0.001
    Stage 1a 604 (30.8) 541 (32.9) 63 (19.7)
    Stage 1b 1207 (61.5) 973 (59.3) 234 (73.1)
    Stage 2 and above 151 (7.7) 128 (7.8) 23 (7.2)
Depression (%) <0.001
    No 598 (30.5) 538 (32.8) 60 (18.8)
    Full-threshold 633 (32.3) 494 (30.1) 139 (43.4)
    Sub-threshold 731 (37.3) 610 (37.1) 121 (37.8)
Anxiety (%) 0.149
    No 587 (29.9) 483 (29.4) 104 (32.5)
    Full-threshold 624 (31.8) 515 (31.4) 109 (34.1)
    Sub-threshold 751 (38.3) 644 (39.2) 107 (33.4)
Bipolar disorder (%) 0.957
    No 1780 (90.7) 1490 (90.7) 290 (90.6)
    Full-threshold 71 (3.6) 60 (3.7) 11 (3.4)
    Sub-threshold 111 (5.7) 92 (5.6) 19 (5.9)
Psychosis (%) 0.204
    No 1862 (94.9) 1553 (94.6) 309 (96.6)
    Full-threshold 44 (2.2) 41 (2.5) 3 (0.9)
    Sub-threshold 56 (2.9) 48 (2.9) 8 (2.5)
Psychosis-like experiences = Yes (%) 356 (18.1) 282 (17.2) 74 (23.1) 0.014
Mania-like experiences = Yes (%) 298 (15.2) 240 (14.6) 58 (18.1) 0.13
Circadian disturbance = Yes (%) 294 (15.0) 244 (14.9) 50 (15.6) 0.791
History of hospitalisation = Yes (%) 346 (17.6) 265 (16.1) 81 (25.3) <0.001
Any childhood disorders = No (%) 1691 (86.2) 1404 (85.5) 287 (89.7) 0.058
Childhood autism spectrum = Yes (%) 56 (2.9) 52 (3.2) 4 (1.2) 0.089
Childhood ADHD = Yes (%) 104 (5.3) 94 (5.7) 10 (3.1) 0.078
Childhood generalised anxiety = Yes (%) 41 (2.1) 32 (1.9) 9 (2.8) 0.439
Childhood depression = Yes (%) 30 (1.5) 24 (1.5) 6 (1.9) 0.762
Family history—bipolar = Yes (%) 154 (7.8) 135 (8.2) 19 (5.9) 0.202
Family history—psychosis = Yes (%) 82 (4.2) 69 (4.2) 13 (4.1) 1
Family history—suicide = Yes (%) 35 (1.8) 28 (1.7) 7 (2.2) 0.715
Family history—depression = Yes (%) 653 (33.3) 542 (33.0) 111 (34.7) 0.604
Family history—anxiety = Yes (%) 302 (15.4) 248 (15.1) 54 (16.9) 0.472
Family history—alcohol = Yes (%) 171 (8.7) 134 (8.2) 37 (11.6) 0.062
Family history—substance misuse = Yes (%) 140 (7.1) 118 (7.2) 22 (6.9) 0.937
Any physical health problems = No (%) 1598 (81.4) 1332 (81.1) 266 (83.1) 0.444
Endocrine problem = Yes (%) 64 (3.3) 50 (3.0) 14 (4.4) 0.292
Metabolic problem = Yes (%) 35 (1.8) 31 (1.9) 4 (1.2) 0.577
Neurological problem = Yes (%) 55 (2.8) 49 (3.0) 6 (1.9) 0.36
Physical health problems—Other = Yes (%) 257 (13.1) 222 (13.5) 35 (10.9) 0.245
Treatment antidepressants = Yes (%) 737 (37.6) 606 (36.9) 131 (40.9) 0.194
Treatment antipsychotics = Yes (%) 239 (12.2) 195 (11.9) 44 (13.8) 0.398
Treatment mood stabilisers = Yes (%) 124 (6.3) 102 (6.2) 22 (6.9) 0.749
Treatment stimulants = Yes (%) 166 (8.5) 152 (9.3) 14 (4.4) 0.006
Treatment psychological therapy = Yes (%) 1101 (56.1) 927 (56.5) 174 (54.4) 0.532

Note. Columns present overall statistics and then statistics split by whether or not patients exhibited self-harm within 6 months of presentation (No vs Yes). P-value is reported for univariate comparisons between downstream self-harm. For categorical variables, the Chi-square test is performed and for continuous variables, the t-test is performed. Bolded text indicates best significant results at P<0.001.