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. 2020 Dec 24;2020:5328031. doi: 10.1155/2020/5328031

Figure 3.

Figure 3

NLRC3 inhibits the deposition of Aβ, decreases the activation of glial cells, and reverses the degeneration of neurons in APP/PS1 mice. NLRC3 colocalize with NeuN. (a) Immunohistochemistry and quantification of 6E10 in brain tissues (magnification ×200; n = 6). (b) Immunohistochemistry and quantification of GFAP in brain tissues (magnification ×200; n = 6). (c) Immunohistochemistry and quantification of Iba1 in brain tissues (magnification ×200; n = 6). (d) Immunohistochemistry and quantification of NeuN in brain tissues (magnification ×200; n = 6). (e) Immunofluorescence and laser scanning confocal microscopy to measure the expressions of NeuN with NLRC3 in brain tissues of each group. NLRC3 and NeuN were labeled by Red fluorescence (Cy3) and green fluorescent proteins, respectively. Data are expressed as the mean ± standard error of the mean (n = 6). ANOVA and Student–Newman–Keuls test were used for these analyses. ∗∗P < 0.01.