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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Eur J Neurosci. 2020 Jul 29:10.1111/ejn.14927. doi: 10.1111/ejn.14927

Figure 6: Inhibition of catecholamine uptake by cocaine is greater in the NAcc compared to the BLA.

Figure 6:

(A) Representative traces of evoked catecholamine release and uptake in brain slices containing the nucleus accumbens (NAcc) at baseline (Pre-Drug) and 30μM cocaine (COC), overlaid. (B) Represented traces from basolateral amygdala (BLA)-containing brain slices at baseline and 30μM COC overlaid. (C) Cocaine (10μM and 30μM) significantly impaired catecholamine clearance in the NAcc compared to the BLA, (p<0.05, and p<0.001, respectively). (D) An increase in NAcc T80 revealed a significantly greater potency of COC in the NAcc, compared to the BLA (p<0.05). NAcc = nucleus accumbens core; BLA = basolateral amygdala; CA = catecholamine; COC = cocaine; *p<0.05; ***p<0.001. N=5 animals/group