Table 2.
Prevalence and concentration of fecal SCFAs in farm and control children.
| Prevalence n (%) |
Concentration, μmol/g Median (range) |
|||||
|---|---|---|---|---|---|---|
| Farm | Control | Farm | Control | |||
| 4 weeksa | ||||||
| Total SCFAs | – | – | 109 (42–220) | 103 (29–269) | ||
| Acetic | 24 (100) | 23 (100) | 90 (34–177) | 81 (20–259) | ||
| Propionic | 17 (71) | 18 (78) | 5.0 (ND–63) | 6.3 (ND–53) | ||
| Butyric | 18 (75) | 15 (65) | 2.9 (ND–37) | 1.1 (ND–30) | ||
| Iso-butyric | 3 (13) | 7 (30) | ND (ND–4.1) | ND (ND–4.0) | ||
| Iso-valeric | 6 (25) | 7 (30) | ND (ND–3.8) | ND (ND–4.4) | ||
| Valeric | 4 (17) | 1 (4) | ND (ND–9.8) | ND (ND–0.4) | ||
| Iso-caproic | 3 (13) | 1 (4) | ND (ND–1.7) | ND (ND–0.3) | ||
| Caproic | 4 (17) | 1 (4) | ND (ND–1.8) | ND (ND) | ||
| 1 yearb | ||||||
| Total SCFAs | – | – | 141 (57–359) | 142 (82–253) | ||
| Acetic | 28 (100) | 36 (100) | 87 (44–221) | 92 (45–154) | ||
| Propionic | 28 (100) | 36 (100) | 28 (3–48) | 31 (8–87) | ||
| Butyric | 28 (100) | 36 (100) | 25 (8–81) | 20 (4–59) | ||
| Iso-butyric | 22 (79) | 29 (81) | 1.5 (ND–4.8) | 1.4 (ND–5.2) | ||
| Iso-valeric | 27 (96) | 35 (97) | 2.2 (ND–7.6) | 2.0 (0.2–6.9) | ||
| Valeric | 24 (86) | 27 (75) | 0.3 (ND–4.8) | 0.3 (ND–3.8) | ||
| Iso-caproic | 5 (18) | 7 (19) | ND (ND–1.2) | ND (ND–0.9) | ||
| Caproic | 5 (18) | 7 (19) | ND (ND–0–3) | ND (ND–0–3) | ||
| 3 yearsc | ||||||
| Total SCFAs | – | – | 157 (71–287) | 152 (62–283) | ||
| Acetic | 19 (100) | 32 (100) | 83 (46–163) | 86 (32–133) | ||
| Propionic | 19 (100) | 32 (100) | 33 (14–49) | 30 (8–66) | ||
| Butyric | 19 (100) | 32 (100) | 26 (6–94) | 28 (7–70) | ||
| Iso-butyric | 19 (100) | 29 (91) | 2.8* (ND–5.0) | 1.6* (ND–5.3) | ||
| Iso-valeric | 19 (100) | 30 (94) | 3.7* (1.3–7.6) | 2.4* (ND–8.8) | ||
| Valeric | 19 (100) | 31 (97) | 2.7* (0.4–6.2) | 1.7* (ND–4.4) | ||
| Iso-caproic | 0 (0) | 3 (10) | ND (ND) | ND (ND–0.3) | ||
| Caproic | 6 (32) | 11 (34) | ND (ND–1.9) | ND (ND–1.3) | ||
*P < 0.05, Chi-squared or Fisher’s exact test for counts, Mann–Whitney U-test for continuous variables.
ND, not detected. Feces analyzed from: a24 (86%) farm and 23 (62%) control children.
b28 (100%) farm and 36 (97%) control children.
c19 (68%) farm and 32 (87%) control children.