Table 2.

Variants observed on contrasting haplotypes identified after Sanger re-sequencing of the 8000 bp genomic fragment defined by rs152730–rs152740 associated with intrapair discordance.

Haplotype at rs152730–rs8044970–rs63982–rs152745–rs152740	Associated with intrapair disease manifestation	rs152730a	rs62029384	rs8044970a	rs8044984	rs80443907	rs152731	rs152732	rs180878	rs152733
TTAGA	Discordant	T	C	T	T	C	T	C	T	T
GGAAT	Concordant	G	T	G	G	T	C	C	T	T
GTCAT	Concordant	G	C	T	T	C	C	T	G	C
Different between TTAGA and GGAAT as well as GTCAT?		Yes	No	No	No	No	Yes	No	No	No

Haplotype at rs152730–rs8044970–rs63982–rs152745–rs152740	Associated with intrapair disease manifestation	rs63982a	rs152745a	rs8062922	rs152744	rs62029385	rs152743	rs152741	rs57406669	rs152740a
TTAGA	Discordant	A	G	C	A	C	G	C	C	A
GGAAT	Concordant	A	A	T	G	T	G	T	G	T
GTCAT	Concordant	C	A	C	G	C	A	T	C	T
Different between TTAGA and GGAAT as well as GTCAT?		No	Yes	No	Yes	No	No	Yes	No	Yes

^ars152730–rs8044970–rs63982–rs152745–rs152740 were used to map the fragment associated with intrapair discordance and define the contrasting haplotypes TTAGA (associated with intrapair discordance) and GGAAT as well as GTCAT (both associated with intrapair concordance); see Table 1.