Table 1.
Percent identity of amino acid sequences between human CoVs and SARS-CoV-2.
| Alphacoronavirus | Betacoronavirus | |||||
|---|---|---|---|---|---|---|
| 229E | NL63 | OC43 | HKU1 | MERS | SARS | |
| Full spike | 31.4 | 29.8 | 30.2 | 29.5 | 34.8 | 76.0 |
| S1 Domain | 31.2 | 25.0 | 23.8 | 23.7 | 28.3 | 60.3 |
| S2 Domain | 35.0 | 33.1 | 42.3 | 41.2 | 43.6 | 90.0 |
| RBD | 24.1 | 27.8 | 23.8 | 29.4 | 21.7 | 73.1 |
| Nucleoprotein | 28.4 | 32.6 | 34.6 | 33.9 | 49.7 | 90.5 |
Alignments between amino acid sequences of all 7 human coronavirus were done for the Full spike, spike domains S1, S2, and RBD and the nucleoprotein (N).