Table 3.
Bone parameters obtained by QUS in the two groups of participants.
| Healthy controls Mean ± SD (95% CI) | ALS Mean ± SD (95% CI) | Healthy vs ALS Mann-Whitney U-test Z* (p) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Total (n = 66) | Males (n = 42) | Females (n = 24) | Total (n = 33) | Males (n = 21) | Females (n = 12) | Total | Males | Females | |
| BUA (dB/MHz) | 128.0 ± 12.7 (124.9–131.2) | 131.6 ± 12.9 (127.5–135.6) | 121.8 ± 9.9 (117.6–126.0) | 113.9 ± 22.5 (105.9–121.9) | 121.2 ± 21.5 (111.4–130.9) | 101.2 ± 19.2 (89.1–113.5) | −3.125 (0.002)** | −1.823 (0.068) | −3.290 (0.001)** |
| SOS (m/s) | 1560.2 ± 42.1 (1549.8–1570.6) | 1566.7 ± 47.5 (1551.9–1581.5) | 1548.8 ± 28.0 (1537.0–1560.7) | 1539.7 ± 59.5 (1518.6–1560.8) | 1559.3 ± 60.2 (1531.9–1586.8) | 1505.3 ± 40.8 (1479.3–1531.3) | −2.316 (0.021)* | −0.707 (0.479) | −3.121 (0.002)** |
| I–stiffness | 101.9 ± 18.7 (97.3–106.5) | 105.9 ± 20.3 (99.6–112.3) | 94.8 ± 13.2 (89.2–100.4) | 86.8 ± 30.8 (75.9–97.8) | 97.1 ± 30.1 (83.3–110.8) | 68.9 ± 23.8 (53.7–84.0) | −2.754 (0.006)** | −1.269 (0.205) | −3.323 (0.001)** |
| T–score | 0.3 ± 1.2 (0.0–0.6) | 0.4 ± 1.4 (−0.1–0.8) | 0.3 ± 0.9 (−0.1–0.6) | −1.01 ± 2.3 (−1.8 to −0.1) | −0.2 ± 2.3 (−1.2–0.8) | −2.3 ± 1.8 (−3.5 to −1.2) | −3.311 (0.001)** | −1.232 (0.218) | −3.897 (0.000)** |
| BMD (g/cm2) | 0.689 ± 0.136 (0.664–0.722) | 0.715 ± 0.151 (0.667–0.762) | 0.643 ± 0.092 (0.604–0.682) | 0.599 ± 0.209 (0.525–0.673) | 0.668 ± 0.207 (0.574–0.763) | 0.477 ± 0.153 (0.379–0.575) | −2.501 (0.012)* | −0.962 (0336) | −3.255 (0.001)** |
*
p < 0.05;
**
p < 0.01.