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. 2020 Dec 18;11:592827. doi: 10.3389/fphar.2020.592827

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Copyright © 2020 Chen, Ding, Yu, Wang, Wan, Hu and Ma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Compounds identification and the effect of the WZYZP on the experimental spermatogenesis disorder model rats. (A) The phytochemical compositions identification in the WZYZP by UHPLC-Q-TOF/MS in the positive ion mode and negative ion mode. (B) Effect of the WZYZP on sperm counts and motility. (C) Effect of WZYZP on serum hormone levels of T, FSH levels were detected with an ELISA assay. (D) HE staining to evaluate the effect of the WZYZP on rat testes histological changes. Above, magnification ×200, 400. (E) TUNEL staining for the evaluation of cell apoptosis. Above, magnification ×200. ^#p < .05 vs. Model group, ^##p < .01 vs. Model group.