Table 2.
Cox proportional hazards analysis for P/R.
| Univariate Analysis | Multivariate Analysis | |||
|---|---|---|---|---|
| HR (95% CI) for P/R | p | HR (95% CI) for P/R | p | |
| Sex (fraction male) | 1.980 (0.861, 4.551) | 0.108 | ||
| Age (years) | 1.020 (0.996, 1.045) | 0.098 | ||
| Visual disturbance | 3.378 (0.797, 14.311) | 0.098 | ||
| Headache | 0.825 (0.361, 1.889) | 0.649 | ||
| Symptoms of sex hormones | 5.792 (2.000, 16.777) | 0.001* | 10.713 (2.884, 39.800) | < 0.001* |
| Incidental | 0.642 (0.152, 2.721) | 0.548 | ||
| Hypopituitarism | 2.772 (1.27, 6.052) | 0.01* | 2.680 (1.121, 6.49) | 0.027* |
| Hyperprolactinemia | 1.162 (0.504, 2.679) | 0.724 | ||
| Non-GTR | 1.311 (0.389, 4.418) | 0.662 | ||
| Successful chiasmatic decompression | 0.400 (0.180, 0.888) | 0.024* | 1.012 (0.404, 2.537) | 0.979 |
| Cavernous sinus invasion (Knosp grades 3–4) | 1.460 (0.647, 3.295) | 0.363 | ||
| Extrasellar extension (Hardy’s grade 3–4) | 1.728 (0.792, 3.768) | 0.169 | ||
| Compression of optic chiasm | 3.354 (0.454, 24.766) | 0.236 | ||
| Compression of the third ventricle | 1.769 (0.74, 4.228) | 0.199 | ||
| Hydrocephalus | 2.117 (0.483, 9.275) | 0.32 | ||
| Giant NFPA (>40 mm) | 2.964 (1.277, 6.883) | 0.011* | 2.061 (0.562, 7.560) | 0.276 |
| Maximum tumor height (mm) | 1.164 (1.046, 1.296) | 0.005* | 1.060 (0.889, 1.264) | 0.518 |
| Tumor volume (cm3) | 1.031 (1.011, 1.051) | 0.002* | 0.988 (0.954, 1.024) | 0.506 |
| SVM score | 10.037 (2.252, 44.740) | 0.002* | 6.879 (1.328, 35.621) | 0.022* |
*Statistical difference (p < 0.05).