Table 1.

Neonatal and pediatric ECLS indications

Indications	Contraindications
Oxygenation index > 40	Lethal chromosomal or other anomaly
PaO2 to FiO2 ratio < 60	Poor predicted neurologic outcome, irreversible brain injury
pH < 7.25	Uncontrolled bleeding
Shock	ICH ≥ Grade III
A-aDO2 > 500 mmHg	Advanced multi-organ system failure
Pplat > 30 cm H2O	Ventilation > 14 days
	Weight < 1–1.5 kg
	EGA < 30 weeks

PaO₂ arterial partial pressure of oxygen, FiO₂ fraction of inspired oxygen, A-aDO₂ alveolar-arterial oxygen gradient, Pplat plateau pressure, ICH intracranial hemorrhage, EGA estimated gestational age