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. 2020 Dec 18;11:605852. doi: 10.3389/fneur.2020.605852

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Copyright © 2020 Li, Chen, Zhu, Tang, Pan, Gong, Xu, Wang, Zhang, Guo, Zhang, Qin, Zhang, Liu, Fei, Pan, Yu and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The mediation analysis by intracranial atherosclerotic stenosis (ICAS) of the association between neutrophil count and clinical outcome [(A) for poor outcome at 90 days; (B) for mRS score at 90 days). a, regression coefficient of the association between neutrophil count and ICAS; b, regression coefficient of the association between ICAS and clinical outcome, using neutrophil count and ICAS as independent variables; c, regression coefficient of the association between neutrophil count and clinical outcome; c′, regression coefficient of the association between neutrophil count and clinical outcome, using neutrophil count and ICAS as independent variables. The percentage difference of the coefficients (1–c/c′) is shown.